Bisphenol-A, is very little still too much?
France has banned it from all food containers while Belgium has limited the ban to certain containers affecting children under the age of three. The endocrine disruptor (ED) in question is Bisphenol-A (BPA), an agent involved in the composition of plastic containers, cans and other food containers as well as dental cement and thermal papers. In 2015, the European Food Safety Authority (EFSA) set the tolerable daily intake at 4 μg/kg. A study (1) by the University of Liège has shown that two weeks of exposure to a dose which is 160 lower than this threshold is enough to disrupt essential neurotransmission systems in the brains of new-born rats.
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(1) Delayed neuroendocrine sexual maturation in female rats after a very low dose of Bisphenol A through altered GABAergic neurotransmission and opposing effects of a high dose, Franssen Delphine et al. Endocrinology 0013-7227, 201