Terme de Glossaire

amyloid plaques 

Also known as senile plaques, these plaques are extracellular pathological aggregates of fragments of the APP protein (Amyloid Precursor Protein) which is present in the membranes of brain cells. With the effects of age and/or illness (such as Alzheimer's Disease), this APP protein is spliced into small fragments (amyloid peptides) which aggregate to form extracellular plaques, compressing the neurons, leading to the malfunctions observed in patients.

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