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Menarche
First appearance of menstruation. The age of menarche, of first menstruation, varies from one country to another. In certain developing countries, young girls who are poor and malnourished may begin to menstruate later than well-nourished girls in America or in Western Europe. Things take place as if a sufficient level of nourishment and supply of energy sent a signal to the hypothalamic centers, indicating that a young girl is ready to go through puberty. Today we know that the signal involves the operation of a hormone produced in fatty tissue, called leptine.
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