Le site de vulgarisation scientifique de l’Université de Liège. ULg, Université de Liège

Glossary

Vous trouverez dans ce glossaire les définitions de termes présents dans les différents articles, classés de manière alphabétique.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
H
habitable Zone

The range of distances from a star at which water can exist in liquid form on the surface of a telluric planet with a sufficient atmosphere. Depending on the distance, a telluric planet can have its surface water in gaseous or solid form respectively.

Hadron

A composite particle (thus not elementary!) formed by an ensemble of quarks, sensitive to strong interaction. There are two types of hadrons, the baryons (such as the protons and neutrons) and the mesons (formed by a quark/anti-quark pair).

Haematite

An iron oxide (Fe2O3) of a steel grey or red colour forming a red powder after grinding (haematite derives from the Greek Haimatos; blood). It is the main iron ore, and the most mined today.

Haemodynamic

That which is connected to blood circulation mechanisms (flow, speed, pressure, etc.)

haemopoietic system

Collection of organs which are involved in the physiological process of producing blood cells (haemocytes).

hair cells

Sensory cells that are situated on a membrane separates the cochlea into two parts. They are put into movement by the sound vibrations in accordance with certain frequencies: those closest to the base of the cochlea are sensitive to high-pitched sounds; those situated in the last part of the spiral are sensitive to low-frequencies (low-pitched sounds). The vibrations received by the cilia that these cells are equipped with are transformed by the auditory nerve into electrical signals that can be interpreted by the brain.

hair follicles

Cavities in which hairs develop by multiplication of cells producing keratins. They are also associated to the sebaceous gland which produces sebum (lubricant).

Halal

From the Arab word meaning ‘permitted,’ ‘lawful’. It designates what is permitted for Muslims, notably in terms of guidelines for food consumption.

Half-life

The time taken for a substance (medicine, radioactive nucleus) to lose half of its pharmacological, physiological or radioactive activity. In particular, half-life is the time necessary for a radioactive element to lose half of its activity through natural disintegration.

Halley's Comet

A young English mathematician, Edmond Halley (1656-1742) took on the task of calculating the orbits of 24 comets. He published the results of his calculations in a dissertation entitled Astronomiae Cometicae Synopsis. In it he notably established that the comets observed in 1531, 1607 and 1682 were in fact a single comet with a periodic orbit. He predicted its return at the end of 1758 and the beginning of 1759, which turned out to be correct. The first periodic comet had just been discovered; Halley’s name was attributed to it. It has a periodicity of 76 years. Its last passage across our skies goes back to 1986, and its next will take place in 2061.

Hamelius, Paul (1868-1922)

Former professor of English language and literature at the ULg. His publications include Histoire politique et littéraire du mouvement flamand (1894) and the Introduction à la littérature française et flamande de Belgique (1921).

Hamstring

Muscle grouping at the back of the thigh, also made up of several bundles, the muscular antagonist of the quadriceps.

hamstrings

muscles at the back of the thigh, starting at the pelvis (at the ischium) and connecting to the tibia. They play a crucial role in running.

Hanse, Joseph (1902-1992)

Former professor of the history of French literature, and of French grammar at the UCL. He co-directed with Gustave Charlier the Histoire illustrée des lettres françaises de Belgique (1948 and 1959) and he edited La Légende d'Ulenspiegel (1959) as well as the complete poetry of Maeterlinck (1965).

Hapsburgs

A Germanic dynasty which reined over Austria (1278-1918), Bohemia and Hungary (1526-1918), Spain and its immense colonies (from 1516 to 1700), and the Netherlands/Belgian provinces (1482-1794). From 1440 onwards, nearly all the emperors of the Holy Roman Empire of the Germanic nation were chosen from within the dynasty. Furthermore, on the abdication of Charles V, the dynasty was split up into two lines, that of Madrid and that of Vienna

harmonics

The harmonics of a fundamental frequency f0 are multiples of this frequency.
For instance, a stimulation frequency f0 of 10Hz (fundamental frequency, also called first harmonic); the harmonics of this frequency are 20Hz (second harmonic), 30Hz (third harmonic), etc.

Haussmann, Georges Eugène (1809-1891)

Haussmann was a high-level French bureaucrat and prefect of the region of the Seine from 1853 to 1870. In this capacity, and at the request of Emperor Napoléon III, he undertook the urban renewal of Paris. Many boulevards and avenues, most of them rectilinear, were created, along with public parks and gardens, all of which followed strict urban guidelines affecting the height of buildings and the styles of façades. Haussmann also rebuilt the system of water distribution and the sewer system. This radical transformation of Paris occasioned the destruction of around 18,000 houses. He became a Senator in 1857 and was eventually named a baron.

Havelaar, Max

One of the main global actors in fair trade. It is also a branch of the international association Fairtrade labelling Organizations International (FLO). Max Havelaar is not the name of the association’s founder, but the title of a novel published in 1860 in the Netherlands by Eduard Dowes Dekker, under the  pseudonym of Multatuli. In it the author denounces the conditions of the peasants on the island of Java (also part of the colony of the Dutch Indies, the current Indonesia), oppressed and exploited by the local Javanese authorities, with the complicity of the colonial authorities. Max Havelaar (MH) is a fair trade certification body: as such MH neither sells not buys anything. It awards its label only to the products which meet the international criteria of fair trade, dealing mainly with good production conditions, a fair price, respect for the environment, etc. Respect for the fair trade criteria is monitored by a team of fifty or so inspectors, which check some 500 producer and plantation organisations in the light of 250 evaluation criteria.

Haversian canal

the Haversian lamellae are layers of concentric bone (osteon) that are formed during bone growth that surround the Haversian canals. These canals contain blood vessels, lymph vessels and nerves.

HDI

Human Development Index, developed by the Nobel-prize winning Indian economist Amartya Sen and his Pakistani colleague Mahbub ul Haq within the UN Development Programme (UNDP). This index takes into account three criteria: life expectancy at birth, adult literacy rate and gross domestic product. The HDI is thus a figure of between 0 (poverty) and 1 (ideal)

Hebb's Postulate

The coordinated activity of a presynaptic ending and a postsynaptic neuron could reinforce the synaptic connections of these two elements.

Hedge funds

Alternative investment funds. The verb 'to hedge' means 'to cover'. Hedge funds are usually not listed on the stock exchange. They seek maximum investment performance through the use of derivative products.

Heimat

A German word which is difficult to translate as it designates at the same time the country one is born in, the country in one which lives and which is far off when one is abroad. It has a strong emotional connotation, to the point that it is similar to both ‘homeland’ and ‘happiness.’

Hellens, Franz (1881-1972)

a Belgian francophone writer – his real name being Frédéric Van Ermengem – who was born and died in Brussels. He has remained one of the major representatives of Belgian literature of the fantastic, as is witnessed by his novel, Mélusine (1920), inspired by a Medieval legend in which a character is condemned to metamorphose each Saturday into a woman-snake: here though, in a strange garden devoid of any vegetation, readers discover themselves in the presence of a naiad whose ‘yellow and glowing body is composed of heavy coins with cemented joints.’ But besides these works where dreamlike impressions predominate, close to Dadaism and Futurist currents, Hellens was also a defender of Belgian literature in the French language, notably through the journal Le Disque Vert which he founded in 1922 and which never departed from a great eclecticism. And it is not his slightest merit having discovered the poet Henri Michaux.

Hematophagic

“Blood-eating”, describes an animal that eats blood.

Hematopoietic stem cell (HSC)

Type of cell at the source of all blood cell lines.

Cofacteur">

A co-factor containing an atom of iron which serves to host a diatomic gas (often dioxygen O2) at the centre of a large organic ring called prophyrin.

heme synthetase

The heme synthetase (also known as ferrochelatase) is the enzyme which condenses porphyrin and the iron atom to form the heme. It acts in the presence of an iron donating co-factor.

hemicellulose

After cellulose, this is the second component of plant cells. It plays a role notably in forming a bridge between fibers and cellulose. 

hemolymph

A fluid which plays the role of blood in arthropods (insects, spiders, etc.).

Hendrix, Jimi (1942-1970)

An Afro-American guitarist and one of the first electric guitar virtuosos. In 1966 he went to London and formed the rock group The Jimi Hendrix Experience. His passionate music shook up in particular the fields of the Woodstock festival inn 1969. He died in 1970, aged twenty-seven.

hepatic decompensation

Hepatic insufficiency is a consequence of cirrhosis of the liver, when the organ can longer perform its multiple functions. Signs of decompensation appear when more than 75% of the liver isn’t functioning anymore.
The symptoms are as follows:
- icterus: yellow discoloration of the skin (jaundice)
- ascites: accumulation of fluid in the abdomen.
- haemorrhaging: due to an insufficiency in the production of blood coagulation factors. Severe digestive haemorrhaging can also occur when varices rupture in the oesophagus, resulting in local hypertension caused by the cirrhosis.
- asthenia and a drop in the immune defence system by a fall in the production of proteins required for this function.
- encephalopathy:  neurological manifestations (confusion, convulsions, coma) associated with the accumulation of ammonia in the blood. This product of the degradation of proteins can no longer be detoxified by the liver and disrupts the functioning of the brain.

hepatocellular carcinoma

Primary liver cancer*, which almost always develops as a result of cirrhosis or chronic viral hepatitis B or C, after a period of evolution of two to three decades. The cancer isn’t the result of metastases but, instead, grows locally in the liver, where it eventually causes end-stage decompensation.  The only real curative treatment is a liver transplant.
On a global level, it is one of the most common cancers.

*Primary cancer means that the tumour originates in the liver itself, as opposed to ‘secondary’ cancer, which refers to the metastases in the liver originating from another cancer, which is frequently the case.

Hepatocyte

Hepatocyte is the name given to the cells in the liver. They are extremely active cells that fulfil numerous roles in the body: they intervene in the metabolism of carbohydrates and lipids, the recycling of haemoglobin, bile production, the production of blood coagulation factors and the proteins necessary for the immune system, and the detoxification of toxic products, alcohol and a great many types of medication.

Hera

The wife of Zeus and the First Lady of Olympus; the protector of marriage and women.

Heracles

The hero of ‘the Twelve Labours’, and whose Latin equivalent goes by the name of Hercules.

heresy

A name derived from the Greek hairesis meaning ‘preference, special  opinion’ and designating a doctrine which issues from within the Catholic Church but which it condemns as conflicting with dogma.

Hergé, real name Georges Remi (1907-1983)

A Belgian comic strip author and cartoonist. Born in Brussels, Georges Remi joined the scouts in 1921, which gave him the opportunity to publish numerous drawings in scout journals: from 1924 he signed these drawings under a pseudonym, Hergé. At the end of his studies he was hired in the subscription department of a Brussels daily paper, Le Vingtième Siècle (20th century). But his career would take off in 1928 when he was asked to create and illustrate a weekly supplement for the young: Le Petit Vingtième (The little twentieth). Tintin and Milou, Hergé’s emblematic characters, appeared in it for the first time on January 10, 1929. The first album of their adventures, Tintin in the Land of the Soviets, appeared in the following year. During the war he worked for the daily newspaper, Le Soir, which caused him difficulties at the time of the liberation, the Brussels newspaper having been in the pay of the occupying forces. After the war, Hergé launched another weekly journal for the young, The Tintin Journal, in which all the adventures of Hergé’s young hero were published. He founded the Studios Hergé in 1950, which would become a breeding ground for the fledgling talents of Belgo-French comic strips.

Hermaphrodite

A being having characteristics of the two sexes. Snails and earthworms are hermaphrodites.

Hermes

Yhe god of transit and mobility, on the Earth as much as between the world of the living and that of the dead.

herpesvirus

A family of DNA viruses (which have DNA in their genetic composition) that cause many maladies in animals and in humans. Among humans, there is oral and genital herpes, chicken pox, Herpes zoster, infectious mononucleosis, etc.( See A vaccine against infectious mononucleosis)

Herri Batasuna

ETA’s political wing, an extreme left organization calling for independence, declared illegal in 2003

Hesiod

Greek poet (8th – 7th century before our common era), the author of Theogonia, a work which features the oldest interpretation of the creation of the world and the genealogy of the divinities of the Hellenic pantheon. He also remains known for his Works and Days, which informs us about the agrarian practices of his era.

Hesse, Hermann (1877-1962)

German novelist, poet, painter and essayist, who then became Swiss, He won the Nobel Prize for literature in 1946 partly for his great work, The game of glass beads, from 1943.

Heterostructure

A heterogeneous structure constructed by superimposing different materials.

Heuristics

From the Ancient Greek eurisko, meaning 'I find'. Heuristics are descriptive rules that can be logically linked together in a problem solving mode (Heuristics-based decision support systems). In contrast to algorithms, or sets of equations, aimed at providing an analytical solution (Model-based decision support systems).

Hexapod

Sub-category of the arthropods, which notably includes insects.

hieratic

A cursive form of the hieroglyphic system. It is the basic system that all scribes use, since the hieroglyphic system is reserved for an elite. Hieratic script allows scribes to write upon things such as wood, papyrus or pottery shards (ostraca). The system was mostly used in administration or in daily life, and continued to be commonly used up until the seventh century B.C.E., when it was further simplified in order to produce the demotic script. A scribe who had to inscribe hieroglyphs upon a monument would recopy them based on notes written in hieratic, or by using painting at an earlier time. Another scribe might make corrections to the work of the first, and at the end of this process, hieroglyphs would be inscribed in stone.

hieroglyph, hieroglyphic sign

A character in the most ancient form of Egyptian writing (used from the fourth millennium B.C.E. through the fourth century C.E.). The hieroglyphic system is figurative, but it combines phonetic and ideographic values in order to transcribe several levels of language, whether phonetic or semantic. In this way, a hieroglyphic sign can have different functions according to its place within a single word. The primary function of the system is to establish individuality, especially with regard to the existing political power, and this explains the monumental character of hieroglyphic inscriptions. Hieroglyphs have to do with kings or with the sacred, and these signs have been simplified in order to function within a simpler system of writing (the hieratic system or the demotic one) – one used more commonly, or used for writing on supports that were less prestigious than stone, such as papyrus. The hieroglyphic system was deciphered in 1822 by Jean-François Champollion.

hierogrammate

An Egyptian scribe who was capable of understanding hieroglyphs and making new inscriptions.

Higgs Peter (1929)

A British physicist born in Bristol in 1929. In 1964, after the Belgian physicists François Englert and Robert Brout, but independently of them, he suggested the existence of a field (called now the Higgs field) which would be responsible for the masses of particles. Homogenous, this field is undetectable. To confirm its existence, physicists try to bring to light the perturbations which result from the excitation of this field: the Higgs bosons.

High Performance Liquid Chromatography (HPLC)

An analytical method of separating components that presents different chemical properties. A sample (a mixture of pigments extracted from sediment, for example) is pushed by a liquid (mobile phase) and kept for a stationary phase which causes a pressure, and separates the components according to their chemical properties creating peaks of different kinds. By comparison with reference standards, the nature of each of these peaks can be identified and studied.

hippocampus

A cortical structure situated in the median region of the temporal lobe which plays a vital role in memory and learning.

Hippocrates

Hippocrates was Greek physician, who was born around 460 B.C. on the island of Kos in the Aegean Sea, to a family of doctors. Many treatises on medicine have been attributed to him. He is known for having revolutionised medicine, by the use of a pragmatic and rational method that ran counter to the religious and magical methods then in use. Hippocratic ethics are explained in a number of the treatises under his name, including today’s Hippocratic Oath. This oath was sworn by his disciples and is still repeated by future doctors today, if in a modified form. The Oath details doctors’ duties, including the privacy of the doctor-patient relationship. Hippocrates died around 370 B.C.

Hirst, Damien

A controversial artist, born in 1965, he was at the forefront of the 1990s Young British Artists innovation and onslaught on established forms of art. This movement was characterised by its independence, but also by its entrepreneurial spirit and media awareness. Hirst’s work challenges the boundaries between art, science and the media. Examples include a cow and her calf sawn in two, both preserved in formaldehyde, as well as medical cabinets and flies and feeding off a dead cow’s head. In 1991, Hirst prepared an installation called In and Out of Love, for which he filled a gallery with hundreds of live tropical butterflies. Perhaps his most famous, or infamous, artwork is The Physical Impossibility of Death in the Mind of Someone Living (1991), a tiger shark in a glass tank of formaldehyde shown at the influential Saatchi Gallery. The title reflects his interest in mortality, a recurrent theme in his work.

Histamine

When an allergic individual is exposed to an allergen (a substance likely to cause an allergy, for example pollen grains), the immune system of the individual in question releases different substances, known as mediators, like for example histamine which are responsible for the appearance of symptoms related to the allergy. In serious cases, the release of a large amount of histamine can cause an anaphylactic shock, that is to say a sudden and drastic lowering of blood pressure.

histology

Science of the study of biological tissues. It is used to study the structure of living organisms and the interactions between their functional elements. It has a very important role in the exploration of pathological processes and their effects.

histones

A family of proteins that DNA winds around in the nucleus, thus compacting it into a much smaller size.

historiography

The art of writing history. Depending on the circumstances, this term can refer to historical work relating to a given era, and even to the reflections of historians on the actual writing of history.

Hittites

A people related to the Indo-Europeans through language, but whose origins are unknown. They conquered Asia Minor during the 26th century B.C. and settled primarily in Anatolia (Turkey). Their civilization lasted up until the 8th century B.C.

HIV (Human Immunodeficiency Virus)

HIV is a virus that weakens the human immune system. The name was chosen in1986. The virus was identified and isolated by a group of French researchers at the Pasteur Institute.

Hobbes, Thomas (1588-1679)

An English philosopher whose thinking, primarily presented in his work Leviathan, was deployed in order to distinguish the state of nature from the political state. Humans living in a dog eat dog condition, it was necessary to control original social violence by a strong power, which does not stem from God but from human beings themselves, concerned to curb this law of the jungle which threatened to devour them one after the other. From this springs a monarch – or a State – looming over a society neutralized by an ‘(imposed) non-aggression pact.’

Holbach, Paul Henry Thiry, Baron d' (1723-1789)

A French philosopher of German origin who participated in the writing of the Encyclopédie_. He attacked the monarchy’s divine right and the Church.

Holocene

A geological era extending back to 10,000 years ago. It was the last interglacial period of the quaternary, the most recent geological period of the Cenozoic era (66 million years ago to the present day), which is itself the most recent geological era after the Paleozoic era (541 million to 252 million years ago) and the Mesozoic era (252 million years to 66 million years ago).

Holographic lens

A holographic lens is a flat lens that uses holographic techniques rather than curved surfaces to deflect rays of light. It can thus be flat, lightweight, and inexpensive. Such lenses have other properties with regard to the various colors of the spectrum.

Holotype

A term used in zoology to designate a specimen which has enabled the definition and description of a given category in the classification of living organisms.

homeostasis

The capacity of an organism to maintain its different constants at normal levels in order to remain in balance.

Homer (8th century B.C.?)

Greek epic poet considered as the author of the Iliad and the Odyssey. The first work composed in 15,537 lines and divided into 24 songs, recounts – close to four centuries after the facts – an episode from the Trojan war (or Ilion). The second, which consists of 12,263 lines and also 24 songs recounts the return of Ulysses (Odusseus) to his homeland of Ithaca at the end of the same war. Recited during festivals and taught to children, these two epics had a great influence in classical Greece and well beyond. They in reality constitute one of the major influences of European culture and literature.

homologous recombination

Mechanism whereby a fragment of DNA inserts itself into a part of the genome where it shares a similar or identical sequence.

Homology

In evolutionary biology, a homology implies an evolutionary link between two features observed in two different species, which is due to the fact that both of them have inherited it from a common ancestor. They can be anatomical, molecular or genetic characteristics.

Homology

Resemblance between two characters observed in two different species, due to the fact that both of them have inherited it from a common ancestor. These characters, called homologues, can be anatomical or molecular (DNA sequences, proteins).

Homoplasy

Similarity of a character across different species which, unlike with homology, do not share a common ancestor.

Homozygous

Said of a gene represented by two identitical allenes, and by extension one speaks of an homozygous individual for this gene.

Homozygous-Heterozygous

Each of our genes exists in two copies, one inherited from the father, the other from the mother. Therefore eye-color is the result of two genes coding eye color... which do not necessarily code for the same color. It is said therefore that the same gene (the one coding color) exists in two forms (or alleles). When an individual possesses two similar variants of the same gene ( both of them code for the color blue for example), it is said to be homozygous. If the gene is present in two different variants, it is said to be heterozygous.

Honeydew

A thick and viscous liquid, made up of aphid excrement.

Horizontal gene transfer

A process by which an organism integrates genetic material from another organism which belongs to the same generation.

Hormone

Chemical substance secreted by specialized cells or by an organ (for instance, a gland), which produces a specific action. Adrenalin, produced by the adrenal glands (which mediates part of the response of an organism to aggressions), and insulin, produced by the pancreas (which activates the use of sugar in the body), are examples of well known hormones.

hormone-dependent cancers

The cancer cells have oestrogen and progesterone receptors.

Horse of Pride (The)

His ‘Mémoires d’un Breton du pays bigouden’ (Memoirs of a Breton from the land of the bigouden), the subtitle of this work, were published by Plon, as part of the famous ‘Terre Humaine’ collection, in 1975. The author, Pierre-Jakez Hélias (1914-1995), tells the story of his life in a parish in the far west of Brittany and, in particular, his childhood and youth during the first half of the 20th century.

HPLC

HPLC is one of the most common techniques used in chemical analysis laboratories. It makes it possible to identify, separate and dose chemical compounds in a mixture. Its great precision enables trace searching and it is possible to couple it with mass spectrometry.

Hubble constant

In cosmology, the Hubble constant is the constant of proportionality between the distance and the speed at which distant galaxies are moving further apart from us. The Hubble constant gives the local local expansion rate of the universe. The further away an object is, the more quickly it is moving away from us. But measurement of the Hubble constant remains delicate because of the difficulty associated with precisely calculating the distance of theobserved objects.

According to the commonly-accepted model, the Hubble constant is currently estimated at around 73 kilometers per second per megaparsec (73 Km/s/Mpc). This means that a body at one megaparsec from an observer is moving away at a speed of 73 Km/s. A body at10 Mpc from an observer is moving away at 730 Km/s.

Hugo, Victor (1802-1885)

A French novelist, poet and playwright. He is considered as the most important Romantic novelist in the French language. His body of work is very diverse: novels, lyric poetry, plays in verse and in prose, political discourses and a vast correspondence.

Victor Hugo is the author of the celebrated Misérables (1862), Notre-Dame de Paris (1831) or the theatre play Cromwell (1827). He was accepted into the Academy of France in 1841 and was forced into exile in 1852 following Louis-Napoléon Bonaparte’s coup d’etat on 2nd December 1852. On his return to France in 1870 he remained until his death a benchmark within the 3rd Republic, but above all a benchmark within literature.

Huizinga, Johan (1872 – 1945)

A Dutch historian specialised in the medieval period. Homo Ludens (1938) is a ground-breaking work on which the different contributors to War and Games based their work. In this work, Johan Huizinga deals with the influence of game on European culture. He saw game as a cultural phenomenon, presenting it as a direct contribution to the development of culture. Civilization was born and developed like a game; human culture emerged from the game and has the characteristic of a game.

Humanism

A movement of thought which, starting from Italy, developed in Europe during the Renaissance period (from the end of the 15th to the beginning of the 17th centuries). The humanists of the Renaissance were erudite, with a thirst for knowledge, a will to make it progress and transmit it in an accessible manner. They affirmed their confidence in the human being, who they placed at the centre of their preoccupations and whose personal development they looked for. The Humanist movement reconnected with the values, the philosophy, literature and art of classical Greco-Roman Antiquity, considered as the foundation of knowledge. But it also proposed new values, rooted in reason, free will, independence, tolerance and an openness of mind. Thanks to the invention of printing (by the German Gutenberg, around 1454), humanism spread throughout the whole of Europe and in particular favoured the emergence of the Protestant Reformation. Amongst the first humanists were Petrarch (1304-1374), Leonardo de Vinci (1452-1519), Giovanni Pico della Mirandola (1463-1494), Erasmus (circa 1467-1536), Machiavelli (1469-1527), Thomas More (1478-1535), François Rabelais (1494-1533) etc. A very great number of the thinkers of later periods staked a claim to this current of thought or can be termed humanists. Amongst them are: Descartes, Montesquieu, Victor Hugo, Emile Zola, Gandhi, Albert Camus, Albert Jacquard, etc.
Modern humanism involves currents of thought which expound the absolute primacy of the human being, the ultimate reference with which to approach other potentially competing values. The flowering of the human being, balanced and in solidarity with others, must be looked for beyond any subjugation and independently of any supernatural reference, all the more so in that human beings are capable of evolving by themselves in a positive manner. Certain contemporary intellectuals nevertheless warn against a possible drift of humanism, which would lead to the human being being considered as a ‘supreme being’ authorised to appropriate nature and exploit it without limit.

Hume, David (1711-1776)

A Scottish philosopher and historian. In his Treatise on Human Nature, his Essays Concerning Human Understanding and his The Natural History of Religion this thinker with a mind pegged to scepticism appears as a surprising wrecker of received ideas. As the knowledge of everything beyond my own being can only come to me through experience, thinking that we can know the reality of facts is nothing but an agreeable illusion: the impressions which are in me, the feelings which jostle around within, are not sufficient to reach the shores of certainty; the causality of things itself, which my reason believes it is perceiving, is just a mirage of habits inherited from my subjectivity. In short we have there gone a long way from idealism to find ourselves at the heart of empiricism.

Huntington’s Disease

Huntington’s disease (or Huntington’s Chorea) is a dominant neurodegenerative disease which is transmitted genetically. It is contracted at adult age, on average at the age of 35, but results from the mutation of a gene at the embryonic stage. This mutation corresponds to an abnormally long repetition of the glutamine (CAG trinucleotide) of the gene coding for the protein called Huntingtin. This protein is present in every cell and has several functions, notably in the transport of molecules and vesicles in the cell, in endocytosis, or during mitosis and neurogenesis.

The people who contract the disease are the victims of choreas (uncontrolled movements). At the same time the disease generates a loss of intellectual faculties leading progressively to dementia. It leads inevitably to death after twenty years, often due to heart failure or suffocation, the patient being unable to control swallowing anymore.

Huntington’s chorea, previously known as St Vitus dance, was described in a precise manner for the first time in 1872 by George Huntingdon. It affects on average 1 person in 10,000, even if there are areas where it manifests itself with greater frequency, notably in Venezuela.

Huntington’s Disease (or Huntington’s chorea)

Huntington’s disease is a hereditary condition caused by degeneration that causes atrophy of the cerebral cortex and the ganglions of its base (masses of gray matter located within the white matter of the brain). This disease is characterized by the progressive development in adults of convulsive movements and a loss of cognitive function (learning ability, intellectual functions in general).

Huygens, Christian (1629-1695)

A Dutch astronomer and mathematician, one of the first real representatives of the modern scientific spirit, both as an experimenter and as a theorist, and author of the first complete treatise on the calculation of probabilities. In astronomy Huygens invented a combination of lenses which eliminated chromatic aberration, and doubled the length of astronomical telescopes, which in addition increased their magnifying power. This enabled him to notably discover the rotation of Mars and its period. He was amongst the first to point out that the stars were other suns, much further away from ‘ours’. He estimated, with remarkable precision for the period, the distance between the Earth and the Sun. In mechanics, he established the theory of the pendulum, which he used to regulate the movement of clocks. We also owe to him the use of a hairspring for watches, the conception of centrifugal force and the definition of the moment of inertia.

hyaluronic acid

Often used to treat wrinkles by means of injection, hyaluronic acid is first and foremost a glycosaminoglycan that is present in synovial fluid. It is one of the main components of the extracellular matrix. It is currently used to treat osteoarthritis of the knee.

hydranencephaly

A pathology resulting from the absence of development of the cerebral hemispheres which are replaced by pockets containing cerebrospinal fluid.

hydrocarbon

An organic substance only composed of Carbon and Hydrogen atoms (for example, petrol, coal, natural gas, etc.). It is called saturated when the chain it is made up of is composed entirely of single bonds. If it contains double or triple links, it is called unsaturated.

hydrocephalus

A severe neurological anomaly which consists of the cerebral ventricles containing the cerebrospinal fluid increasing in volume.

Hydrogenation

procedure which consists of fixing hydrogen atoms on the double bonds of unsaturated fatty acids. That raises their degree of saturation and melting point. It is this procedure in particular which allows liquid vegetable oils in their natural state to be rendered semi-solid, for example from the point of view of using them in margarines. These fats are abundantly used in the agrofood sector (sandwich spreads, chocolate, ready made meals, pastries, etc.).

Hydrolysis

Chemical decomposition of a substance through the fixing of water, thanks to the H3O+ et HO- ions. The hydrolysis of saccharose gives us glucose.

Hydroxyapatite

Principal mineral component of dentin and bone, whose chemical formula reads Ca10(PO4)6(OH)2.

hydroxylation

A chemical reaction which consists of adding a hydroxyl group (-OH) to a molecule. In the case of vitamin D, after it has been integrated by means of food for example, it is transported to the liver where it is hydroxylated by the enzyme 25-hydroxylase, which fixes a hydroxyl in the place of the H of carbon 25, forming 25-hydroxy vitamin D also called calcidiol.

hyoid bar

Similar to a “tongue”, although it does not have the same function as in humans. It supports the branchial basket. It allows the fish to vary the volume of its mouth to adapt the force of its food intake. 

Hyperglycaemia

An abnormally high concentration of sugar in the blood.

hyperthyroidism

An endocrine gland located at the front of the neck, the thyroid regulates various hormonal systems thanks to the secretion of two hormones, triiodothyronine (T3) and thyroxin (T4). Hyperthyroidism is caused by an excessive concentration of one or both of these hormones in the blood. The most frequent symptoms are tachycardia, diarrhea, weight-loss and insomnia. The opposite symptoms are associated with hypothyroidism including tiredness, memory loss and weight increase.

hypoacousia

Reduction in hearing ability.

hypodermis

Under the epidermis and the dermis, the hypodermis is the deepest layer of the skin. It serves as an interface between the dermis and the moveable structures situated underneath it (muscles, tendons). It also protects the body from physical blows, temperature variations and acts as a store of adipose (fat).

hypolipidaemia

Pathological reduction in the lipid level in the blood.

Hypomorph

Said of a mutation which leads to the expression of a protein which retains part of its activity.

Hypophyseal dwarfism

The term “dwarfism” refers to a lack of growth which is more than 20% below normal average size. There are numerous varieties of dwarfism. Among them is hypophyseal dwarfism, which is an harmonious dwarfism. This means that the different parts of the body remain in proportion, and it results from the lack of secretion of the hypophyseal (or pituitary) gland and more specifically, the front part of it, the anterior pituitary, also known as the adenohypophysis. The hormones produced by this part of the hypophysis are primarily: FSH (follicle-stimulating hormone), LH (luteinising hormone), ACTH (adrenocorticotropic hormone), GH (growth hormone) and TSH (thyroid stimulating hormone).

Hypophysis

Also called the pituitary gland, hypophysis is an endocrine gland situated in a small bony cavity at the base of the brain. It is made up of different types of cells which secrete hormones which are indispensable for the correct development and functioning of the body.

Hypostatic Union

Since the Council of Ephesus (431) this expression designates the union of the divinity and humanity in the person of Christ.

Hypothalamus

A small cluster of cells at the base of the brain, in the middle of the skull and which control the body’s essential functions such as hunger, wakefulness or temperature.

hypoxia

Term which comes from the Greek hupo: under, and Oxus: oxygen. A reduction in the quantity of oxygen distributed by the blood to the tissues.



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